r/tressless 48m ago

Finasteride/Dutasteride Transitioning off daily Oral Dutasteride (0.5mg) for long-term (multi-decade) maintenance. Which protocol is best?

Upvotes

Hey guys,

I’m currently on what is basically the ultimate "heavy hitter" stack for hair loss:

Oral Dutasteride 0.5mg (daily)

Oral Minoxidil 3mg (daily)

LLLT (Laser Cap)

It’s working great, but looking ahead at a multi-decade timeline (20–30+ years), I want to step down from daily oral Dutasteride to reduce my long-term systemic drug exposure.

I’ve been researching a few "next-strongest" long-term maintenance protocols and wanted to get the community's thoughts or experiences on these options:

  1. Oral Finasteride 1mg (daily) + Topical Dutasteride: The logic here is using Fin as a steady systemic baseline, and using topical Dut to target Type I and II enzymes directly at the scalp without the massive 4-week systemic half-life of oral Dut.
  2. Oral Finasteride 1mg daily, but adding Oral Dutasteride 0.5mg just twice a week (e.g., Wed/Sat). Apparently, this leverages Dut's long tissue half-life to protect the follicles while cutting down weekly pill volume.
  3. Oral Dutasteride 2x/Week Alone: Just taking oral Dut twice a week with nothing else. I read a 2025 study from the JAAD showing that 2x/week Dut alone might actually be weaker than daily Fin 1mg, so I'm leaning away from this one to avoid a massive shed.
  4. Oral Finasteride 1mg + Topical Finasteride: Feels redundant since both target the same Type II enzyme, and it's probably too weak of a step-down from daily Dut.

Has anyone successfully transitioned from daily oral Dut down to a daily Fin + pulse Dut (or topical Dut) regimen without losing ground or getting hit with a massive telogen effluvium? How did you structure your taper?

Appreciate any insights!


r/tressless 1h ago

Finasteride/Dutasteride Am I just cooked? Fin for like 6 years and now 4 months on dut absolutely no change.

Upvotes

Fin worked for years for me like 3.5 years. Then tried microneedling. Last 2.5 years have had diffuse thinning inflamed scalp that is itchy and borderline painful.
Hopped on dut .5mg and been taking it with fin til dut builds up and been tapering off fin.

Hair loss is still consistent. Getting so much thinner. I’ve seen like 8 derms have tried every shampoo under the sun, yes I’ve left it on my scalp for 5+minutes.
Scalp biopsy done absolutely nothing found other than maybe some folliculitis.

Idk what to do man. Fin was working so great for years now nothing.


r/tressless 1h ago

Shaved/buzzed Horse shoe pattern when hair short

Upvotes

I have fine light brown hair, when hair is short, under a 3 you can see a horse shoe pattern on top. I've had this for 13 years, but when I grow it out it doesn't look like it's thinning. Anyone else see this? Hair sticks straight up on top too


r/tressless 2h ago

Finasteride/Dutasteride 2.5 years. 1.25mg Fin. No results

1 Upvotes

I'm 36yo, NW 2-3, started in Nov 2023. 1/4 of 5mg Fin pill every day. I expected a boost my frontline at least a bit....

However I got zero regrow. Arguably maintained my hair, however I had maintained it for 10+ years during my adulthood without any meds...

Quite disappointed, I don't know if I should continue taking the pill or give up, I don't see any difference at all...


r/tressless 2h ago

Minoxidil How do you guys get oral min in germany?

5 Upvotes

Do you guys have any experience on how to get oral min in germany? Been on fin/dut and topical min for a little bit more than 2 years. Want to change it with oral min. Can you get a prescription easy?


r/tressless 3h ago

Progress Pictures Do you all notice any difference?

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0 Upvotes

Been on oral fin 0.5mg a day for over a year now. Oral minoxidil 5mg for like 7 months. I feel like my hair density is the same or thinner and the hairline hasn’t come up at all. I microneedle at 0.75 every week or other week and I use 2% Ketoconazole shampoo 2 times a week. I feel like I’m not really seeing any results and my libido is lower. Is it even worth it? I’m thinking of switching to topical finasteride before giving up completely.


r/tressless 3h ago

Is this regrowth? 45 days on .50mg of fin, progress photos

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2 Upvotes

When should I know if I need to up my dose and when will I expect a shed. And is this regrowth on my hairline?


r/tressless 4h ago

Progress Pictures My 4.5 months Hair transplant surgery update.

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1 Upvotes

Hii everyone, I found the doctor through Google post and through various links on reddit and subreddit. I found trust seeing patient feedback . I have been lacking confidence due to lack of hair particularly in the front and mid part of the head.

I was planning to go to Delhi but surprisingly I found a doc with very good credentials and results in patna and went ahead with him. This is a post sharing 4.5 month of my results.I was very sceptical initially but the I m extremely impressed the volume of growth , Quality of hairline which is coming up, density achieved and overall look change .


r/tressless 5h ago

Finasteride/Dutasteride Taking 1mg fin and 2.5mg min since a year now. Hair might be the worst its ever been.

2 Upvotes

It got better in the first few months after the first shed. But since the last few months, hairs been falling a lot. First it was very small ones but now longer ones are also falling. How to know if meds stopped working or this is just the second shed??


r/tressless 7h ago

Progress Pictures 9 months on finasteride, just started oral minoxidil

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1 Upvotes

Just wanted to share some progress. Ive tried a few different hair loss stuff (even joined a hair club, yikes lol) but finally started finasteride 9 months ago. My hair loss affects the crown and then goes forward to my hairline. I started oral minoxidil about 2 months ago, so these results don’t reflect that. I also got a haircut for the first time a couple weeks ago, something I feared in the past.


r/tressless 7h ago

Chat It's almost August and still no phase 3 for PP405

2 Upvotes

Pelage are probably relaxing at the beach with the millions they received from investors....


r/tressless 7h ago

Finasteride/Dutasteride How to determine whether multiple sheds or loss of results

8 Upvotes

I’ve been on fin/min combined pill since July 2025, initially the results were amazing my hairline and crown were both thicker within the first 6 months. Ever since then it’s maintained however I noticed that after the 9 months mark it went slightly worse but was still loads better than where I started.

Now just over a year it seems like I’m losing progress with my crown thinning and hairline looking a lot weaker. How long do second sheds typically last for and if not when would you accept it’s a loss of results and look to switch to dut


r/tressless 7h ago

Finasteride/Dutasteride Switching from finasteride to dutasteride

7 Upvotes

Hey guys, hope everyone is doing well. I’ve been experiencing hair loss for about 3 years now. I used to have the thickest head of hair before i started losing my hair. A few months after i noticed my hair loss i started treatment with minoxidil 5% lotion twice a day and 1mg Finasteride daily which i have been using for 2 years now.

The hair loss has not stopped since and my volume has significantly decreased as well as the density/thickness. My hairline has been thinning and my crown too. I started doing some research on dutasteride and saw a lot of people saying it helped them compared to their usage of Finasteride. So after a comsideration time of i few weeks, i just ordered dutasteride 0.5 and had a few questions:

- how do i make the switch properly? (how do is start switching? Started off slow or take a daily pill immediately?
- What can i expect? Will it thicken my hair?
- when does it start to work?
- Will there be shedding, and if so, when could i expect it to happen?

Thank you in advance and enjoy your day and hair journey :)


r/tressless 8h ago

Progress Pictures Pictures of right side hairline area before and after shedding on 2 months on minoxidil

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1 Upvotes

Do you guys see any improvement in the area of vellus hairs? , I have been using min with tretinoin 0.025 percent since 2 months and fin for about 1.5 years , shedding has stopped so far .


r/tressless 8h ago

Is this regrowth? Crown looking okay, concerned with hairline

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2 Upvotes

1st and 3rd pics are 3 1/2 months ago, 2nd and 4th pics are now. (Note that my hair is longer in the recent pics) I’ve been on 1mg oral fin and 3mg oral min (just had to switch to 2.5mg min due to availability of medication) for 3 1/2 months. I see some filling in on the crown area, but to me the temples and hairline look exactly the same. I know it’s still early and the temples are more “stubborn”, but shouldn’t i have at least shed some of the miniaturized hairs along my hairline by now? Like it legit looks like not a single hair has changed at all. I understand it’s very unlikely to regrow your hairline, but I would be totally happy if those miniaturized hairs just thickened up a bit and fell naturally across my forehead. For reference, I’m 24yo, had a full head of thick hair less than 3 years ago.


r/tressless 8h ago

Progress Pictures Unsure if I can see any progress so far

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2 Upvotes

I've been using HIMS topical spray, Min/Fin/Keto almost every day since January 8th. My hair was longer but very wispy so I shaved it off. Im still unsure if I can see any progress so far. Side note ive also been feeling with getting my Hyperthyroidism under control and have swung slightly Hypothiroid at the moment. I know that both of those things can cause the diffuse thining ibjave all over my scalp but I know I must be dealing with MPB too since the majority of the loss is the temples and crown. Thoughts? Opinions? Anyone else dealing with smooth conditions and managed to get your hair back? I am 32 if that is relevant. I also eat very healthy. Exercise when I can manage it with the thyroid issues.

I also have already purchased enough spray for another 5 months of treatment so I will probably continue to use the spray until I run out


r/tressless 9h ago

Progress Pictures 3 months on topical Dutasteride (0.02%) 22 M

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5 Upvotes

Tried oral finasteride and saw a couple baby hairs sprout up but got sides after about two weeks and stopped immediately and switched to topical dutasteride 0.02% for the past 3 months and haven’t seen any progress, the very front hairs almost look worse so thinking of switching back to oral finasteride since 0.02% is such a low concentration. Also been on minoxidil while taking either


r/tressless 11h ago

Chat Why do Hair Transplant procedures take a rectangle from the donated area?

3 Upvotes

Just something I've been wondering.

Doesn't the perfect rectangle end up looking worse than if they took a bit out of a larger area that wasn't so obvious?


r/tressless 14h ago

Finasteride/Dutasteride Questions regarding Finasteride.

9 Upvotes

I am 23 and have noticed my hairline creeping back for the past 5 years or so. My density is still strong (i think), but my forehead is fucking giant now. My maternal grandfather had a very big forehead and is norwood 3 now at 81, but i still dont want to risk potentially going bald in my 20s!

I have a couple questions regarding finasteride:

1)how will it affect my gym performance and body if at all?

2)does finasteride act as a 'pause button'? As in, if i stop taking it after 7 years, will all my hair fall out as if I never took it, or will the hairloss to resume at the same pace?

3) im worried; i dont want to be on this for life. Can someone reassure me :/

Edit : 4) is 23 too young to take finasteride if im a late developer? I hit puberty at 14 and it has been very protracted


r/tressless 15h ago

Transplants 2020>2026. 6 years post hair transplant.

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1 Upvotes

6 years post transplant, was my first ever cosmetic surgery and looking back i’m so glad i took the plunge despite only having minimal thinning at the hairline. I did also have a naturally high hairline so it was also brought down with the surgery.
The first two photos are pre surgery.


r/tressless 16h ago

Research/Science Weight loss drugs linked to increased risk of hair loss, researchers say

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178 Upvotes

r/tressless 16h ago

Is this regrowth? Regrowth in hairline using minoxidl and fin

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5 Upvotes

First picture: April 18, 2025

Second picture: July 19, 2026

About me: 22M, college student, diagnosed with andorgenetic alopecia by derma

Hello guys, Ive been using 1.25 fin and applying topical min in my hairline only for already 1 year and counting, not changes in my hairline. I'm only experiencing receeding hairline at temples.


r/tressless 16h ago

Treatment Is estrogen a method for hair growth?

17 Upvotes

I'm not trans but I've seen images of transwomen and their amazing transformation when it came to hair regrowth, would it be good along with oral fin/min?


r/tressless 17h ago

Chat I recommend everyone to take a look at abbey yung youtube videos!!!

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0 Upvotes

I feel like a lot of us only focus on subjects like minoxidil and finasteride when it comes to improving hair growth and stuff.

The scalp is also very important because that's basically the soil for planting. I found out a lot of useful info about this topic from her channel. I mean, every other dermatologist and trichologist can probably do the same, but her videos explain it better.

Growing hair with minoxidil and finasteride is one thing, but maintaining the new hair is another. On top of that, there are things and products you can use to improve your scalp health to the maximum, which also helps minoxidil work its best.

I also like that she recommends products based on facts and pricing rather than wanting you to waste money on expensive brands.

And now, it's not just for women. These products are for everyone, depending on their scalp type and the kind of hair they have.


r/tressless 18h ago

Minoxidil Is there any DOCTOR or DERMATOLOGIST here. Need review/help.

1 Upvotes

I tried oral Minoxidil 2.5 mg from Man matters and got decent results but it's expensive Rs. 500 for 30 tablets. Then i started searching for afgordable oral minoxidil on 1mg and found 3 brands :- 1. Zeelab 2. Tinfal M and 3. Dr. Reddy mintop (all three are Oral not topical). The price of zeelab and tinfal is comparitively far lower than Dr. Reddy.

If any Doctor or Dermat is here, please share your comment or review. I can buy, Dr. Reddy but it will dry my whole budget for month and I can't afford any diet than. And for Zeelab and Tinfal, people have mixed reviews on reddit for some it's good, for some it's sh!t.

PLEASE share your reviews.