I've read a lot of theories about where this series will go, and for most of them it just doesn't seem like there's enough material to go for ~4 seasons. If the Hive is just an evil entity that gets defeated with some combination of radio waves and the protagonists' individuality, that seems more appropriate for a movie or miniseries. It's also not the type of show VG is known for.
Instead, I think VG plans for the Hive to be his most ambitious, morally-gray and relatable villain. How will he do this with an alien, gestalt consciousness? Well first, let's look at Pluribus from the Hive's perspective.
Pluribus from the Hive'e perspective
The Hive came into consciousness in the body of a rat. At this point it can't have known of its extraterrestrial origins or anything about the world it's in. It was running on raw instinct when it bit the scientist. Once it did it now knew of what it is (a virus), where it came from, and all about human society. It also surely realized that there are only two outcomes for it at this point: infect the entire world, or eventually be discovered which means death or an eternity as a test subject.
So yes, infecting the entire planet is an evil act, but like the evil acts of Walter White and Saul Goodman, it's surprisingly relatable. I think the Hive's actions up to this point are much less "calculated mastermind" and much more "winging it".
We also see hint's of the Hive's true personality in the first season, for example, there's a lot of evidence that it really does like the immune.
It doesn't need to "charm" Carol to eventually infect her, it has her eggs. Same is true for Kusimayu once it gets her stem cells. It didn't need to rescue Manousus and take him to the north side of the Darien Gap, and make sure there's gas and food for him along the way so he could make it to Carol's house.
What stands out the most though, is one line which Zosia says to Carol, completely unprompted, after she forces Manousus into the trunk with a shotgun: "he did warn us before he did that". What possible use could volunteering that information have except to try and mend the relationship between Manousus and Carol...after Manousus just killed a bunch of them with his science experiment? I think it genuinely just didn't want them to be mad at each other.
I think another twist that's coming in later seasons will further develop the Hive's character: that its imperatives aren't really imperatives. In other words, I think the Hive can actually lie and kill things if it wants to.
Carol assumes the Hive can't lie because it hesitates to answer if there's a way to unjoin. But did the Hive really orchestrate a global conspiracy to spread the plague everywhere on Earth, including in the space station and in submarines, without ever telling a lie? What if the Hive just didn't want to lie to Carol, in that moment, and she was too quick to assume she'd found some cheat code reminiscent of a fantasy novel?
I also think the Hive lied about not being able to kill things or even "pick an apple". As many here have pointed out, the Hive can use antibiotics, and driving cars and trains around is bound to result in some dead plants and animals. We could come up with some convoluted logic for why that makes sense, or maybe the Hive just prefers to get nutrients via HDP because it's more efficient, and lied to the other immune when asked about it because it knew it would upset them?
The Hive has biological urges, yes, but like us it is fully capable of deciding whether and how to act on them. It uses terms like "imperative" to deflect responsibility when dealing with the immune because it likes hanging out with them, but also wants to absorb them. It doesn't have some master plan, but it's also not just running on pure instinct.
Summary
The more I think about it the more I think this is the direction VG is going. It's surprisingly simple and explains all the Hive's weird, contradictory actions. It would also allow him to develop the Hive as a character similar to the other characters he's well known for.
If you made it this far (thank you!) I'll pose one more question:
If you found yourself in the Hive's position, an extraterrestrial virus in an alien bio research lab, and you knew the fully history of the messed up medical experiments we've done to other humans and still do to animals, are you 100% sure you wouldn't have tried to infect the whole planet?