Will Reta decrease running performance?

[u/Traditional-Yam6959]

Hi, I’m a 20F looking to lose about 5 kg using retatrutide. I’m a long-distance runner and have completed multiple marathons, so running is a big part of my life, but I’m aiming to lean out slightly.

I took my first injection about a week ago and have already noticed a drop in my running performance, especially a slower pace. From what I understand, this can happen due to factors like increased heart rate, reduced calorie intake, and lower glycogen stores.

My question is whether this is just temporary while I’m on the medication, or if it could have longer-term effects. Once I stop retatrutide after a few months, is it likely that my performance will return to baseline or even improve, or could this dip in performance carry over?

Would really appreciate hearing from anyone with experience or insight on this.

[u/Dear-Response-7218]

Why even consider a glp1 if you’re distance running? They are meant for obesity, not a 5KG loss for all the reasons you mentioned. Reta hasn’t been studied enough to understand the long term effects.

[u/Traditional-Yam6959 → u/Dear-Response-7218]

Yea I know, but I’m struggling with overeating if I try a natural deficit, just thought it might help with decreasing the mental energy I have to put in it

[u/Unhappy-Revenue-3903 → u/Traditional-Yam6959]

Tirzepatide may help more with the overeating, but it’s a dual agonist. Where Reta is a triple. I have used both. I do like Reta better. But I am not sure what happens when you stop.