r/ResearchCompounds 3d ago

Discussion Will Reta decrease running performance?

Hi, I’m a 20F looking to lose about 5 kg using retatrutide. I’m a long-distance runner and have completed multiple marathons, so running is a big part of my life, but I’m aiming to lean out slightly.

I took my first injection about a week ago and have already noticed a drop in my running performance, especially a slower pace. From what I understand, this can happen due to factors like increased heart rate, reduced calorie intake, and lower glycogen stores.

My question is whether this is just temporary while I’m on the medication, or if it could have longer-term effects. Once I stop retatrutide after a few months, is it likely that my performance will return to baseline or even improve, or could this dip in performance carry over?

Would really appreciate hearing from anyone with experience or insight on this.

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u/javierf720 3d ago

It raised my resting heart rate a good bit and has made some efforts harder for me. I know you said reta but checkout the zepbound athletes subreddit,it'll give you decent insight in glp impacts on athletic performance.