r/PCOSloseit Sep 08 '25

PCOS and GLP-1s

49 Upvotes

Many of us are using or considered using GLP-1s to manage our PCOS. We've also noticed more and more posts and comments about it.

Head over to r/PCOSglp1 - a new subreddit to discuss all things PCOS and GLP-1s.

GLP-1 topics will still be allowed here. Though, we think a separate subreddit is also beneficial as you can get better advice and more relevant information when all the members are there for the same subtopic.

In the future, we may direct glp1 posts and topics to that subreddit.


r/PCOSloseit 7h ago

Anybody else REALLY struggling?

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85 Upvotes

I've lurked here for a long time and I'm at the end of my rope and hoping someone maybe has had success with similar circumstances as I find myself in.

I'm (almost) 34F/5'5"/239, diagnosed at 21. Hormonal BC feels like it was a trigger for me as I put on over 60 pounds in less than 6 months shortly after starting. I have a history of disordered eating (WW at 14, anybody?) and so I try not to track cals too often, because I get overly restrictive and obsessive about it, but I have a good idea of what I'm eating since I still measure and eat the same foods often.

Here's what I've done or am doing:

- strict keto for 18 months (ob/gyn recommended, I lost 50 pounds, messed up my gut when I'd never had issues before, and was an absolute bitch because it was miserable. Gained it all back and then some.)

- metformin 500mg at night, I see my endo in a month and we'll decide if we want to up my dose

- wearing a CGM to see what spikes my blood sugar

- worked with a nutritionist for the last year and a half

- take berberine, Ovasitol plus, vit d + k, methyl b12, magnesium glycinate

- strength train 2-3 times a week, we have a Peloton and I ride 3-4 times a week as well (sedentary job, unfortunately)

- watch my carbs, pair carbs with fat and protein always, tons of water, only 1 cup of coffee, limit added sugar, higher protein, always eat breakfast, etc etc

My ovaries are clear of follicles currently, and I'm still having insanely irregular cycles (currently cd 65 and counting šŸ™ƒ) and I have worked so incredibly hard to go from 243.2 to 238.9 since mid-January. No recent labs because my ob and endo agree that they're not necessary at the moment since obviously my hormones are fucked up. Does anyone have any similar experience?? A ton of my coworkers are ordering glp1s online and asking chatgpt for their doses and have lost a bunch of weight. I am so close to throwing in the towel and trying it, or microdosing or SOMETHING, but I'm terrified of potential side effects and losing muscle and bone mass because that's the one thing I actually have going for me. I feel like I've wasted my 20s and so far my 30s with hating how I look, because I have. I'm treated for anxiety and depression already but I literally don't know what else to do short of starving myself and depriving myself of good food, which I love. Sorry for how long this is, I just don't know what else to do, and I hate that my daughter is seeing me work so hard and still struggle so much. Thanks in advance, cysters!


r/PCOSloseit 12h ago

Told my PCP I’m taking a GLP-1 during my annual and then I got charged $500 for ā€œnutrition consultationā€ - beware

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19 Upvotes

r/PCOSloseit 12m ago

19f, 5’9, 277lbs, and feeling like i will never lose weight

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• Upvotes

hi all, i came here because i figured you guys would know best. i was diagnosed with pcos when i was 17 and have been tryna to lose weight since. within the past 2 years ive lost approximately 17 pounds. i want to lose more, my goal weight it 170-180lbs and then i want to explore my options from there. i cant take a pill/shot because im at high risk for thyroid cancer and i have gastrointestinal issues as it is (yay me!). ive been scared to go the gym because im self conscious of how i look and dont have the extra cash for it right now. i take mili 0.25 mg to manage pcos and thats about it. im very close to just giving up on trying to lose weight all together.

i would love guidance on meals that you’ve enjoyed on you weight loss journey, workout tips/plans, literally anything and everything will help! ty for reading ā¤ļø


r/PCOSloseit 19h ago

New to Metformin - any tips?

11 Upvotes

Hi! I've finally decided to start taking control of my health, and as someone who was "anti medication, I can do this naturally" for the longest time, I finally decided to go on Metformin for my insulin resistance and pcos/pmos after being stuck in the same loop for years. I know it's not a weight loss drug, but I am hoping it will help regulate my sugars and help with my food noise. A small weight loss to kickstart would be a nice bonus. I have 100+ to lose, and will also be calorie tracking/food weighing, limiting processed sugars, increasing protein, and slowly introducing strength training.

I'm a tad nervous to begin, as I've read some GI horror stories. šŸ˜… I've been prescribed 500mg twice a day. Any tips on it would be great! Also, regarding B12, do any of you take a supplement alongside it? Thanks!


r/PCOSloseit 16h ago

Walking 20 min when i wale up reset my mood , but i have noticed that i ate more and crave more on the days i walk fasted . Is it related to my pcos and my binge eating disorder ? Or it’s not related ?

5 Upvotes

r/PCOSloseit 10h ago

Are my weekends what’s keeping me at maintenance instead of my PCOS?

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0 Upvotes

r/PCOSloseit 12h ago

Diabetic safe recipes

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1 Upvotes

r/PCOSloseit 18h ago

PCOS

2 Upvotes

Hello. I was told I had PCOS since a few years ago. I am 24 y.o and also have insulin resistance. I have high testosterone and irregular menstruation. I have been to a lot of doctor's, gynecologists, endrocrynologists and with no results. They always prescribed me contraceptives but they're not the solution of the problem. I don't know what to do anymore. I don't drinks sugary drinks and sugar, don't eat fast-food, eat complex carbs, veggies daily and no result.


r/PCOSloseit 1d ago

New Doctor said stop taking metformin and inositol

38 Upvotes

So I talked to a new gynaecologist and told her I am taking metformin 500mg a day with split of breakfast and dinner that makes 250mg each .
My periods are delayed 2 days today.

She said STOP TAKING METFORMIN OR IT WILL MAKE YOU DIABETIC.

My awe for her was like what??! I know the fact if I don’t take metformin my insulin is skyrocketing and I eat every possible thing. With metformin it’s easier for me to control my craving.

How can deal with this delayed period and weight loss which is stuck on down 61kg down from 64kg. It has to be 10kgs down as let height of 4.10. I am lost and I am tired


r/PCOSloseit 17h ago

Switching to Organic or Whole Foods Quality?

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0 Upvotes

r/PCOSloseit 1d ago

PCOS and Wegovy?

3 Upvotes

Hey everyone,

I keep hearing that Mounjaro is superior to Wegovy, I did lose a bit of weight when taking it but found I had to go to 10mg pretty quickly because I seem to have a horse like tolerance to medication in general. I can’t afford that high a dose so it’s off the table :(

Wegovy is cheaper here and just looking for some success stories/words of advice. I’m desperate to lose weight again, I’m struggling so badly because of my shift patterns partly but the insane food noise and craving for sugar is killing my motivation and my bank. I now take metformin but am not seeing much help with the insulin resistance (may need to move up a dose). I’m in the UK - help a girl out!

Thanks! :)


r/PCOSloseit 23h ago

Everything has Failed

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1 Upvotes

r/PCOSloseit 1d ago

Pcos & Pregnancy

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1 Upvotes

r/PCOSloseit 1d ago

Any GLP1 or weight loss remedies that arent expensive?

1 Upvotes

Hi guys pcos girly here also started birth control recently looking for cost effective weight loss remedies or shots/pills that isnt over $100 a month. im 5'5 pushing 180 biggest ive been in awhile just need something to keep weight off.


r/PCOSloseit 1d ago

advice?

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1 Upvotes

r/PCOSloseit 1d ago

Seeking PCOS Participants for a Graduate UX Case Study

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1 Upvotes

r/PCOSloseit 1d ago

Android food diary recommendations? Plus... has anyone with PCOS struggled despite trying everything?

2 Upvotes

Hi everyone,

I'm looking for two bits of advice.

Firstly, does anyone have any recommendations for a good Android food diary app? I'm getting frustrated because LoseIt! seems to have inaccurate nutrition entries. For example, it logged 100 g of purple sweet potato with the skin on as having 0 g fibre, which I know isn't right. I'd like something with a more reliable food database.

Secondly, I'm just feeling a bit defeated with my weight loss.

I was diagnosed with PCOS when I was 9 and I'm about to be 37 this year and I genuinely feel like I've tried everything over the years. I've done keto, veganism, calorie counting, different healthy eating approaches, and nothing seems to result in weight loss. I have been the same weight most of my life. I gained 11lbs from wedding stress in 2018 and never could lose it. My weight consistently stays at 179lbs.

I also wear a Garmin watch, do cardio every day, I do weight lifting, walking, and log my food as accurately as I can. Yes, I weigh my food too. I know Garmin calorie estimates aren't perfect, but even accounting for that, I feel like I'm putting in a lot of effort without seeing the results I'd expect.

Has anyone else with PCOS been in the same position? If so:

What finally worked for you?

Are there any Android food diary apps you'd recommend with a more accurate database?

Did you discover anything that made a bigger difference than diet and cardio alone?

I'd really appreciate hearing from people who've been through this, because at the moment it feels like I'm working hard but getting nowhere.


r/PCOSloseit 1d ago

What counts as a period?

2 Upvotes

Iā€˜m 25, with ā€lean PCOSā€. I recently went to my doctor for treatment options and she said as long as I was getting a period every three ish months I didn’t need any treatment.

But what I’m wondering after the fact is, what actually counts as a period? Does brown spotting for two days count and reset the clock, or is that not a ā€œperiodā€ enough? Do I need actual red blood and cramping?

Also, are we really not doing anything for our hormone levels?! I feel like mine are high, what are yours?

Total testosterone: 119 ng/dL

AMH: 30.54 ng/mL

FSH: 5.8 IU/L

LSH: 22.3 IU/L


r/PCOSloseit 2d ago

After years of struggle I’m finally seeing results

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163 Upvotes

After 5 years of struggling with my weight trying all the diets, walking, cardio, trying metformin etc I’m finally seeing results after 9 weeks of strength training 2-3x week and loosely tracking calories/ prioritising protein. Feels so amazing to see these results after almost giving up (I got referred to weight loss dr and my appt is this week- but now I’m considering cancelling). The pic with the microphone is from March… the other one was taken today. The March pic I was wearing shapewear, today’s one I am not


r/PCOSloseit 1d ago

inositol and body fat redistribution

2 Upvotes

i searched and couldn't find something pertaining to this.

i started inositol 2 months ago and metformin about 1 month ago. i've lost a few pounds, but i am noticing the fat around my belly and butt has started moving to my "love handle" area.

my clothes are fitting weird and it's starting to appear like my butt is shifting up 3-5 inches.

has anyone dealt with this before? is there something i can do? i am due to get bloodwork done next month, so i plan on asking for hormonal levels, is there anything i should specify?

(i do not have my ovaries anymore, so my uterus and adrenal glands produce a lowered amount of estrogen and i don't do hrt)


r/PCOSloseit 1d ago

Participate in a study about PCOS

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1 Upvotes

r/PCOSloseit 1d ago

Pcos and trizeptide (HELPPPPPPPPPPP)

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1 Upvotes

r/PCOSloseit 2d ago

Day One of Zepbound!

2 Upvotes

I think I fucked up by not holding the button down but lesson learned.

Starting weight: 315lbs (I think? I don’t have a working scale so I’ll have to check later.

Goal weight: 130lbs.

I’m also prescribed metformin and bought inositol.

So excited to finally FINALLY kickstart my journey.