I’m going off to college soon to major in biochem. I would like to know which laptop has the longest life span and can efficiently run different programs for my major.

I was debating whether to get a MacBook Air or pro with a M4 chip. If you anyone has other brands to recommend, please tell me 😋

The body tightly regulates its internal vitamin D production from sun exposure, stopping further synthesis once adequate levels are reached to prevent toxicity. However, this safety mechanism only applies to sunlight. Taking high dose supplements bypasses this natural control, making toxicity possible. I’m not too worried about toxicity here. My main concern is when to take supplements to actualize the best stores of vitamin D.

If I take 6,000IUs in the morning and then am in the sun around noon, will my body not create vitamin D given that I had a 10x the daily need for vitamin D bolus just a couple hours before? Would it be better to be in the sun first, let my body produce vitamin D and then supplement if I am looking to maximize how much is in my body?

Trying to decide what classes to take?

Want to know what the job outlook is with a biochemistry degree?

Trying to figure out where to go for graduate school, or where to get started?

Ask those questions here.

Hey everyone! We are Microbes in 1 Minute (M1M). Our goal is to improve scientific communication related to the world of microbes, by producing short-form content related to Microbiology. We are looking for anyone interested in learning about microbes, writing super short scripts, or helping us edit these short videos. We are an international team (currently) composed of PhD students from Harvard and Universidad Autónoma de Madrid, and an undergraduate at University of Southern California (and hopefully you next!). If you’re interested please contact us by filling out this form: https://docs.google.com/forms/d/e/1FAIpQLScbPVGLcO8DuNzC7GBDJHsnAYwqksYnS\\_kXNQ-pz1C7EYNBuA/viewform?usp=header, or attend our biweekly meeting next week (Thursdays at 3pm EST)!

Thank you for your interest,

—The M1M team

All I hear about the fact that we’ve solved the folding problem, but the only thing that I’ve heard about what it will lead to is the classic ditty: “it’s going to lead to new applications in x and y, and it’s going to lead to faster b and c.”

So can someone please explain what being able to make entirely new proteins from scratching a computer will lead to, but in the terms of sea change in industries and complete changes in capability that are only capable because of this technology?

Thanks

hey guys, I randomly came into this guy recently

https://www.youtube.com/watch?v=HZfHLhcc7wo&t=2819s

I knew the Electron transport chain well before but this is that extra level in fine-tuning some details. I've already watched all the vids from topics I liked from this channel, was wondering if you had anything like this. Clear, in depth, not entertainment but 100% educational oriented.

I am enjoying 'The Gene' by Siddhartha Mukherjee atm, but I would also like to know some other books that uses slightly easier language so please give me some recommendations!

Idk if this is the right subreddit but for a project I need to cut a crab shell on various pieces, is there a chemical reaction that could help me soften the shell or do something so it doesn’t break when I try to cut it? Thank youuuu

I am learning about topoisomerases and their role in supercoiled DNA relaxation. Feel free to post images or videos to show how this happens.

Hey, so I'm in 5th sem of my biochem degree. Next week my department is organizing this stuff where there will be poster presentation, quizzes and stuff. I haven't taken part in anything like this, nor I have been keeping up with the science news stuff also. But I'm realising it's imp and so I have some questions

-Is it too late to try being part of it now? Not only I'm in 3rd year but it only has like 7 days now.

-And that I'm an undergrad and i dont have my own research, so do i just pick some research paper and present that?

-If it is so.. Then is it just one paper or to combine stuff from more than one?

-How do I actually do it... If broadly the topic is cell biology.. Do I read some journal or just go to science direct web and just search cell bio ( for my assignment I try like this... But get overwhelmed and will then just ai

it... Which I hate to do.. And also want to improve this)

My only goal is to present good stuff... I don't want to get first place in the first time... But whatever I want to present I want it to be good, actually relevant and interesting. how do I even find it?

I'm also scared of questions that follow..

Should I be doing it?

During my last year of high school, life did me dirty, I developed severe depression (the reason is not important), and my cognitive skills tanked. Before that, for 17 years, I was the "genius" kid. Top of my class. Everyone expected a bright future. In my third-world country, the system only gives you one exam year to decide everything—no retries. I scored the lowest grade of my life. Couldn't get into med school. Ended up in chemistry.

I grieved not being a doctor thousands of times. Felt cheated, inferior, like something was stolen from me. After graduation, I worked in a hateful job for 3 -4 years, then got a scholarship to Europe—did my Master’s at a prestigious uni, worked as a researcher at a top-ranked lab for a year. For the first time, the "doctor complex" faded. Life felt bearable.

Then the contract ended. No option but to go back home.

I've been applying to PhDs and industry jobs across Europe since. Came close three times. Nothing. I'm now 30, living in my parents' house because I never managed to save money, no job. My mind won't stop torturing me with "what ifs." I keep comparing myself to my doctor friends my age, they have stable careers, clear paths, decent pay. And me? Thousands of applications with no payoff.

I spent the last six months preparing for PhD interviews. Real effort. And I keep thinking — I could've used that effort studying for a new exam if I'd been a doctor. But why should I have had to? I deserved to study what I loved and what I was capable of, not what a two-week exam at 17 decided for me. And I'm still paying for it 12 years later.

I feel like my career is ruined. Completely drained, barely have the energy to keep applying, though I still do — I love science, I just hate how unfair and limited this field is. I need stability and money, and I know people with less potential than me who have both, just because life didn't screw them over at the wrong moment.

Even abroad, my closest friends were MDs, and they got the easy visa routes, the fast permanent residency. Me? A researcher with no leverage, knocking on a thousand doors just to be "eligible" to work. Had to move back to a country I don't even like, couldn't secure a permit or sponsorship in Europe.

Does anyone else deal with this kind of comparison? How do you let go of the past, stop measuring your life against the one you think you should've had, and actually accept it?

I was originally going to major in Biochem, and while I love the theory I really really don't like lab work, so I decided not to. I still want to be knowledgable in it, so where do I start?

For context: I took Higher level Chemistry and Biology in the IB, if that helps.

Have you read a cool paper recently that you want to discuss?

Do you have a paper that's been in your in your "to read" pile that you think other people might be interested in?

Have you recently published something you want to brag on?

Share them here and get the discussion started!

As a person who enrolled for BSc Biochem with the first sem starting on Monday, If my aim is to do MSc In Germany or Austria or other good European country, how should I plan my 4 years and what should be my major goals that I should focus on. A brief opinion would be helpful so I can get an idea about this.

Hi all, I am looking for good advanced books about protein chemistry, (also about protein formulations in pharmaceuticals).

What would be your top 5 choices?

I have MSc in biochemistry (ehm, protein chemistry specifically), so I am looking for good reference materials (i.e. not Voet or Lehninger).

Thank you ☺️!

Hey everyone! So I will be graduating this fall (in december) with 3.65 degree in biochemistry. I work in a chemical engineering wet lab right now and although I enjoy it, I have enjoyed my computational biology classes more and could see myself doing computational work in the future. The one problem is I don't have significant experience working in bioinformatics/computational biology or related fields. Is it absolutely essential that I go to grad school to get a job? And do I need to get a PhD so I don't have a ceiling in industry work? It's just been a struggle looking at jobs online and reading other peoples comments seeing that you need significant experience in the field before you even apply/ that the job market is extremely rough these days. I'm honestly not sure what to do, as I wouldn't mind going to grad school, but its just expensive and a big commitment to make. Any advice helps, thanks.

I have some containers filled with remnants of soy lecithin. Would it be possible to add water and lye to saponify the lecithin to clean these out? I’ve read it’s not a true fat so it may not work. Any other ideas for cleaning up this stuff?

Thanks

Hello!

I'm applying for a PhD heavily based on Biochemistry (protein synthesis, enzymes, crystalography etc) but i come from a bit of a different background and only had biochem for the first year in college so i would love to revise the fundamentals. Any good Biochem book i can get for this? There's tons of it obviously but it's hard to separate wheat from chaf. If its relevant i am based in Europe.

Thanks!

Just wondering what the theoretical expected outcome is

Podcast with Dorothy Chou, who ran Google DeepMind's Public Engagement Lab for nine years. She now advises DeepMind and chairs UCLPartners, an organization connecting new technology to the UK's National Health Service. 

Covers:

• What made AlphaFold possible in the first place and how we can replicate its success in other domains
• Why neither venture capital nor governments can fund biology on biology's actual timeline, and Dorothy’s proposed solution
• Why AI could help redirect money the ideas that will actually help people the most, not just the ones that are easiest to fundraise for 
• How AI companies are about to repeat the public engagement mistake the biotech industry already made once
• Her advice for young people who feel like they're not the expert in the room

‍

I did this just before my first sem Biochemsitry BSc which begins shortly, I am 18yo. Please provide your feedbacks for this project. How it works:

> One can log-in into the web app
>then they can enter as many DNA sequence they want line by line
>a button with TRANSLATE can be clicked
>the dna sequences are translated into corresponding protein sequences

NOTE:

Invalid DNA sequences are detected by this tool
Invalid bases are detected and the tool displays error

Thank you for spending your time here on my silly project. Please leave your comments.

Trying to decide what classes to take?

Want to know what the job outlook is with a biochemistry degree?

Trying to figure out where to go for graduate school, or where to get started?

Ask those questions here.

During urea estimation with dam diacetyl monoxike method , what happens if I just leave them in room temp for 30 to 60 minutes without water broth . is there a possibility of colour change to slight pink during that time , anyone?

I'm a layman who knows essentially nothing about biotech, but I'm curious about a specific question that I'm hoping I could get some insight on from people in the space.

Say we were able to ask a machine learning model, or whatever other system, to spit out a protein with specific desired properties/functions: how much would this tech affect the world we live in, across all fields, including medicine and agriculture? How far are we, at a best guesstimate, from actually achieving this? Plausibly within the next 10 years? More like 20? Maybe almost certainly not for at least another 50 years?