r/AutoImmuneProtocol 18h ago

Sugar alcohol in medication

3 Upvotes

Hi, all. I was recently prescribed LDN, and the filler contains a mix of ingredients I was told were hypoallergenic: isomalt, glyceryl, poloxamer, sodium fumarate. I was preparing to start but just realized that isomalt, being a sugar alcohol, isn't AIP-compliant. Now, I'm not sure whether I should take it.

I have autoimmune neuroinflammation, likely CIRS, and am extremely sensitive to foods. My diet at the moment almost solely consists of chicken and olive oil. When I've tried to reintroduce non-AIP foods such as cacao, egg yolk, and nuts, I developed horrible depression, brain fog, and DP/DR for weeks. Don't get me started on grains and dairy. However, I've also heard that gellan gum isn't compliant, yet I take a DAO enzyme that has it, which I think I tolerate fine. I'm not sure where isomalt would stand on the sensitivity scale. Is it only non-compliant because it's synthetic? Because in that case, I suppose the medication itself wouldn't be either...

The pharmacy had told me previously that they could formulate another bottle with different ingredients if needed. Should I reach out?

Edit: I'm also on a therapuetic keto diet and worry a little about the blood sugar impact, but I think the effect should be negligable... although if anyone has knowledge of this, feel free to weigh in.